Long-chain fatty acid triglyceride (TG) metabolism disorder impairs male fertility: a study using adipose triglyceride lipase deficient mice
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منابع مشابه
CD36 deficiency in mice impairs lipoprotein lipase-mediated triglyceride clearance.
CD36 is involved in high-affinity peripheral FFA uptake. CD36-deficient (cd36(-)(/)(-)) mice exhibit increased plasma FFA and triglyceride (TG) levels. The aim of the present study was to elucidate the cause of the increased plasma TG levels in cd36(-)(/)(-) mice. cd36(-)(/)(-) mice showed no differences in hepatic VLDL-TG production or intestinal [(3)H]TG uptake compared with wild-type litterm...
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Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme mediating triglyceride (TG) hydrolysis. The lack of ATGL results in TG accumulation in multiple tissues, underscoring the critical role of ATGL in maintaining lipid homeostasis. Recent evidence suggests that ATGL affects TG metabolism via activation of peroxisome proliferator-activated receptor α (PPARα). To investigate specific eff...
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STIMULATED INSULIN SECRETION Marie-Line Peyot, Claudiane Guay, Martin G. Latour, Julien Lamontagne, Roxane Lussier, Marco Pineda, Neil B. Ruderman, Guenter Haemmerle, Rudolf Zechner, Érik Joly, S. R. Murthy Madiraju, Vincent Poitout and Marc Prentki Molecular Nutrition Unit and the Montreal Diabetes Research Center, CRCHUM; Departments of Nutrition and Medicine, University of Montreal, Montreal...
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ژورنال
عنوان ژورنال: MHR: Basic science of reproductive medicine
سال: 2017
ISSN: 1360-9947,1460-2407
DOI: 10.1093/molehr/gax031